Peritoneal dialysis (PD) allows people with kidney failure to manage their treatment at home. One important part of PD is selecting the right solution to help control fluid and waste in the body. If you're a patient, caregiver, or clinic provider, this guide will help explain the differences between commonly used PD solutions like Dianeal 1.5%, 2.5%, 4.25%, and Extraneal 7.5%, and when to choose each one based on patient symptoms.
Understanding PD Solutions PD solutions help remove waste and excess fluid from the body. The two main types are:
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Dextrose-based solutions (Dianeal): Contain glucose (sugar) to draw fluid out.
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Icodextrin-based solutions (Extraneal): Use a starch-based compound for slow, steady fluid removal.
Each strength serves a different purpose:
Dianeal Solutions (Dextrose-Based)
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1.5% (Yellow bag)
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Gentle fluid removal
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Used for patients with stable fluid status
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Common for daytime exchanges
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2.5% (Green bag)
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Moderate fluid removal
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Used for mild fluid overload, slight swelling, or minor weight gain
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4.25% (Red bag)
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Strongest dextrose concentration
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Used for severe fluid overload, breathing difficulty, or high blood pressure due to fluid buildup
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Not for daily use due to risk of dehydration and high glucose exposure
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Extraneal (7.5% - Purple bag)
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Made with icodextrin
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Best for long dwell times (8-16 hours)
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Ideal for:
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Chronic fluid overload
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Patients with poor response to dextrose-based solutions
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Lowering sugar exposure in diabetic patients
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Note: Not suitable for short dwell exchanges; may interfere with some glucose monitors
Quick Reference: What to Use When?
| Symptom or Condition | Recommended Solution | Reason |
|---|---|---|
| Mild fluid retention | Dianeal 2.5% (Green) | Balanced fluid removal |
| Severe swelling or SOB | Dianeal 4.25% (Red) | Fast, aggressive removal |
| Long-term fluid buildup | Extraneal 7.5% (Purple) | Sustained removal overnight |
| High blood pressure | Dianeal 2.5% or 4.25% | Reduce fluid load |
| Low blood pressure | Dianeal 1.5% (Yellow) | Avoid over-drainage |
| Diabetic patients | Extraneal (Purple) | Lower glucose absorption |
Helpful Tip: Always consult your nephrologist or PD nurse before changing solutions. They’ll assess your fluid status, weight changes, and symptoms to determine what’s right for you.
Comfort Matters Too At MandMcares, we know comfort is part of care. Our adaptive clothing and PD accessories are designed to keep you warm, supported, and confident during your treatments.
🛍️ Visit our store for PD belts, warm hoodies, and treatment essentials: Shop MandMcares
Final Word The strength and type of PD solution you use can significantly impact your treatment success and how you feel day to day. With the right solution and supportive care, you can stay in control of your health journey.
Need a helpful visual or educational resource for your clinic? Contact us to collaborate.
MandMcares – Thoughtful, Practical, and Comfort-Focused Solutions for PD Patients.
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